Strains of Cordyceps militaris grow on a silkworm pupa. The fungus has been found to contain chemicals that carry anti-cancer benefits.[Photo provided to China Daily] Chinese scientists have found evidence that a fungus used in traditional Chinese medicine widely sought by the public for its healing powers, also carries anti-cancer benefits. The scientists found there was an interaction between two anti-cancer compounds in the fungus Cordyceps militaris. The first, cordycepin, was noted in Cordyceps militaris in 1950, but how it interacted remained unknown. The second, pentostatin, was first identified from a bacterium and was developed as a commercial drug to treat leukemia and other cancers in the 1990s. For the first time, we decoded the biosynthesis mechanism of cordycepin in the fungus, and during the research we unexpectedly discovered pentostatin, said Wang Chengshu, head of the research team at the Institute of Plant Physiology and Ecology, a branch of the Shanghai Institutes for Biological Sciences of the Chinese Academy of Sciences. These two compounds coexist in fungal cells in the form of a protector and protege - that is to say, cordycepin is synthesized with the coupled production of pentostatin to protect the stability of the former, he said. Their research also showed that the fungus initiates a detoxification process when the cordycepin in the body reaches an excessively high level, which can be toxic. It reminds us that excessive intake of the fungus may not be healthful, Wang said. A paper about the team's findings after nearly eight years of research was published on the website of the international journal Cell Chemical Biology on Thursday. Cordyceps militaris, bright orange-yellow mushrooms sold as a fresh supplement for soups and stews, is a much more affordable alternative to caterpillar fungus. However, in the research, we've proved that neither of the compounds is produced in caterpillar fungus, Wang said. Cordyceps fungi are popular in China for their widely believed immunity-enhancing and energy-strengthening properties. Their uses in medical treatment date to the Compendium of Materia Medica, a book widely deemed the encyclopedia of traditional Chinese medicine written in the Ming Dynasty (1368-1644). There have been long-running arguments as to whether such fungi are antibacterial or anti-cancer, and people use them based on experience in most cases. It's a major advance that our team scientifically proved that Cordyceps militaris really carries such properties, said Guo Jinhua, Party chief of the institute. cheap custom wristbands
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A finless porpoise is taken for a physical examination in Jiangxi province. The species has been classified as critically endangered.  Recent research may provide good news about the endangered species, as Cheng Si and Liu Kun report from Wuhan. The rate of decline in the number of finless porpoises in the Yangtze River may have slowed in the past six years, according to experts in the field. Wang Ding, a researcher at the Chinese Academy of Sciences' Institute of Hydrobiology, said official statistics will not be released until March, but recent research may indicate positive steps in the conservation of the species, which is classified as critically endangered by the International Union for Conservation of Nature. However, the river's environment is still deteriorating as a result of overexploitation of natural resources, while waterway regulations and water-related construction projects pose great threats to the porpoise's natural habitat, Wang said. His comments came at the end of a scientific survey of the porpoise that was launched in Wuhan, Hubei province, on Nov 11. The survey, conducted by CAS, reviewed the status of the species in the Yangtze River, its major tributaries and two lakes called Dongting and Poyang. Financed by the World Wide Fund for Nature and charities in Hubei, the 40-day survey covered 3,400 kilometers of water, from Wuchang, Hubei, to Shanghai. In 2006, a survey found that there were 1,800 finless porpoises in the wild. However, the number had fallen to 1,405 by 2012, indicating an annual rate of decline of 13.7 percent. The number is now estimated to be less than 1,000, and the ministry placed the species under the highest level of State protection in May. Freshwater species The finless porpoise, a member of the toothed whale family, is so named because it lacks a true dorsal fin. Females produce a calf once every two years, and have a gestation period of 10 to 11 months. The species makes both high-and low-frequency tones and uses ultrasound to communicate.
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